Effect of Bifidobacterium Longum Bb536 Plus Lactoferrin in the Treatment of Irritable Bowel Syndrome. A Double Blind Clinical Trial
نویسندگان
چکیده
Several studies have reported that the Intestinal microbiota of IBS patients is altered and differs from healthy people. Such condition of dysbiosis, associated with physical or psychological stress, may increase the intestinal barrier permeability, hypersensitize the afferent fibers of the enteric nervous system, and thus contributing to the clinical manifestations of the syndrome. Bifidobacteria are normally present in the human intestine where they exert a fundamental role. Presence of Bifidobacteria in patients with Irritable Bowel Syndrome (IBS) is decreased and their use as probiotics has been indicated to re-establish eubiosis in this condition. Previous Japanese studies have reported the efficacy of the probiotic Bifidobacterium Longum BB-536 to normalize bowel frequency and stool consistency in young adult [1,2] and elderly subjects [3]. Mini Review Volume 6 Issue 4 July 2017 DOI: 10.19080/ARGH.2017.06.555691 Adv Res Gastroentero Hepatol
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